ChemInform Abstract: Synthesis of Boc- and Z-Protected Amino Acid Fluorides Employing DAST as a Fluorinating Agent.
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چکیده
منابع مشابه
ChemInform Abstract: Direct Synthesis of β- Hydroxy-α-amino Acids via Diastereoselective Decarboxylative Aldol..
A straightforward metal-free synthesis of anti-β-hydroxy-r-amino acids is described. The organic base-mediated decarboxylative aldol reaction of cheap, readily available r-amidohemimalonates with various aldehydes afforded under very mild conditions anti-β-hydroxy-r-amido esters in high yields and complete diastereoselectivity. Simple one-pot subsequent transformations enabled the corresponding...
متن کاملnano-rods zno as an efficient catalyst for the synthesis of chromene phosphonates, direct amidation and formylation of amines
چکیده ندارد.
Aqueous Microwave-Assisted Solid-Phase Synthesis Using Boc-Amino Acid Nanoparticles
We have previously developed water-based microwave (MW)-assisted peptide synthesis using Fmoc-amino acid nanopaticles. It is an organic solvent-free, environmentally friendly method for peptide synthesis. Here we describe water-based MW-assisted solid-phase synthesis using Boc-amino acid nanoparticles. The microwave irradiation allowed rapid solid-phase reaction of nanoparticle reactants on the...
متن کاملZ-Protected Glutamic Acid-Based Biodegradable Thermoplastic and Thermosetting Polyesters: Synthesis and Characterization
Biodegradable polymers were formed from N-benzyloxycarbonyl-L-glutamic acid with the comonomers ethylene glycol, diglycidyl ether of 1,4-butanediol, and diglycidyl ether of bisphenol A. The three polymers were a linear and a rosslinked heterochain polyester and a crosslinked polyester that contained aromatic units within its network chains. The thermoplastic resin and the soluble fractions for ...
متن کاملSynthesis and oligomerization of Fmoc/Boc-protected PNA monomers of 2,6-diaminopurine, 2-aminopurine and thymine.
A Boc-protecting group strategy for Fmoc-based PNA (peptide nucleic acid) oligomerization has been developed for thymine, 2,6-diaminopurine (DAP) and 2-aminopurine (2AP). The monomers may be used interchangeably with standard Fmoc PNA monomers. The DAP monomer was incorporated into a PNA and was found to selectively bind to T (ΔT(m)≥ +6 °C) in a complementary DNA strand. The 2AP monomer showed ...
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ژورنال
عنوان ژورنال: ChemInform
سال: 2001
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200103181